Research2021-11-04T12:24:47-05:00

Review the Research

Get summaries of key research on vitamin D and COVID-19

Study Summaries

COVID-19 Disease Severity and Death in Relation to Vitamin D Status among SARS-CoV-2-Positive UAE Residents

COVID-19 Disease Severity and Death in Relation to Vitamin D Status among SARS-CoV-2-Positive UAE Residents. Take Home Message In a multicenter observational study of 464 COVID-19

The association between vitamin D levels and the clinical severity and inflammation markers in pediatric COVID-19 patients: single-center experience from a pandemic hospital

The association between vitamin D levels and the clinical severity and inflammation markers in pediatric COVID-19 patients: single-center experience from a pandemic hospital. Take Home Message

Low Circulating Vitamin D in Intensive Care Unit-Admitted COVID-19 Patients as a Predictor of Negative Outcomes.

Low Circulating Vitamin D in Intensive Care Unit-Admitted COVID-19 Patients as a Predictor of Negative Outcomes. Take Home Message The main findings of this single-center retrospective

Lack of association between vitamin D insufficiency and clinical outcomes of patients with COVID-19 infection

Lack of association between vitamin D insufficiency and clinical outcomes of patients with COVID-19 infection. Take Home Message In a cross-sectional retrospective study of 153 hospitalized

Low plasma 25(OH) vitamin D level is associated with increased risk of COVID-19 infection: an Israeli population-based study

Low plasma 25(OH) vitamin D level is associated with increased risk of COVID-19 infection: an Israeli population-based study Take Home Message Plasma 25(OH)D levels < 75

Vitamin D deficiency as a predictor of poor prognosis in patients with acute respiratory failure due to COVID-19

Vitamin D deficiency as a predictor of poor prognosis in patients with acute respiratory failure due to COVID-19 Take Home Message Vitamin D deficiency and obesity

Ongoing Studies

Explore current trials being conducted around the world focused on vitamin D and COVID-19.

Title Status Conditions Interventions Location
Vitamin D Supplementation in Pregnant Women at Risk and COVID-19 Not yet recruiting • Pregnancy Complications
• Covid19
• Vitamin D supplementation in pregnant women • Maria Jose Aguilar Cordero, Granada, Spain
Clinical Outcomes of High Dose Vitamin D Versus Standard Dose in COVID-19 Egyptian Patients Recruiting • Covid19
• Corona Virus Infection
• Cytokine Storm
• Vitamin D Deficiency
• Teachers Hospital, Cairo, Egypt
Effect of Vitamin D on Hospitalized Adults With COVID-19 Infection Recruiting • Covid19 • Cholecalciferol
• Placebo
• CHU Liège, Liège, Belgium
Baseline Vitamin D Deficiency and COVID-19 Disease Severity Recruiting • Vitamin D Deficiency
• Covid19
• Vitamin D • Parkview Medical Center, Pueblo, Colorado, United States
Efficacy of Vitamin D Treatment in Mortality Reduction Due to COVID-19. Recruiting • SAR
• SARS Pneumonia
• Vitamin D
• PLACEBO
• Joaquín Durán Cantolla, Vitoria-Gasteiz, Alava, Spain
Vitamin D3 Supplementation to Prevent Respiratory Tract Infections Recruiting • Respiratory Tract Infections
• Covid19
• Flu Like Illness
• Vitamin D supplementation • Cooper University Hospital, Camden, New Jersey, United States
Trial of Vitamin D to Reduce Risk and Severity of COVID-19 and Other Acute Respiratory Infections Active, not recruiting • Covid19
• Acute Respiratory Tract Infection
• Vitamin D • Queen Mary University of London, London, County (optional), United Kingdom
Effect of Vitamin D on Morbidity and Mortality of the COVID-19 Recruiting • COVID-19 • Cholecalciferol • Hospital Universitario Central de Asturias, Oviedo, Asturias, Spain
Vitamin D and COVID-19 Trial Recruiting • COVID-19 • vitamin D
• Placebo
• Brigham and Women’s Hospital, Boston, Massachusetts, United States
High Dose Vitamin-D Substitution in Patients With COVID-19: a Randomized Controlled, Multi Center Study Recruiting • Covid19
• Vitamin D Deficiency
• Corona Virus Infection
• ARDS
• Coronavirus
• SARS-CoV Infection
• Single high dose vitamin D
• Placebo
• Treatment as usual vitamin D
• Cantonal Hospital Aarau, Aarau, AG, Switzerland
• Cantonal Hospital Baselland Liestal, Liestal, BL, Switzerland
• Cantonal Hospital St. Gallen, Saint Gallen, SG, Switzerland
Vitamin D Status and Immune-inflammatory Status in Different UK Populations With COVID-19 Infection Not yet recruiting • Covid19 • no intervention • GSTT NHS Trust, London, United Kingdom
Efficacy of Vitamin D Treatment in Pediatric Patients Hospitalized by COVID-19 Recruiting • Covid19
• Vitamin D
• Children, Only
• Cholecalciferol • Hospital Centro Medico Nacional Siglo XXI, Mexico City, Distrito Federal, Mexico
Tele-health Enabled Clinical Trial for COVID-19 Not yet recruiting • SARS-CoV Infection • Vitamin D3 or Placebo
• Doctella telehealth monitoring
• Northwestern University, Chicago, Illinois, United States
N-terminal Pro B-type Natriuretic Peptide and Vitamin D Levels as Prognostic Markers in COVID-19 Pneumonia Recruiting • COVID19 Pneumonia • Pro BNP , Vitamin D • Kasr Alainy Cairo University, Cairo, Giza, Egypt
Prevention of COVID-19 With Oral Vitamin D Supplemental Therapy in Essential Healthcare Teams Recruiting • COVID-19 • Placebo
• Vitamin D
• CHUM, Montreal, Quebec, Canada
• CHU Sainte-Justine (CHUSJ), Montreal, Quebec, Canada
Vitamin D Supplementation in the Prevention and Mitigation of COVID-19 Infection Recruiting • COVID-19
• Vitamin D Deficiency
• Respiratory Viral Infection
• Daily Vitamin D3
• Daily placebo
• Bolus vitamin D3
• Bolus placebo
• Medical University of South Carolina, Charleston, South Carolina, United States
The Effect of D3 on Selected Cytokines Involved in Cytokine Storm in the Covid-19 Uninfected Jordanian People Enrolling by invitation • Cytokine Storm • Vitamin D3 • Mahmoud S Abu-Samak, Amman, Jordan
Influence of Military Preventive Policy for reCruit Training on COVID-19 Seroconversion Recruiting • SARS-CoV Infection
• Vitamin D Deficiency
• Covid19
• Acute Respiratory Tract Infection
• Vitamin D • Headingley and City campuses, Leeds Beckett University, Leeds, Yorkshire, United Kingdom
• Infantry Training Centre Catterick, Catterick Garrison, United Kingdom
Short Term, High Dose Vitamin D Supplementation for COVID-19 Active, not recruiting • COVID • Vit D • Deptt of Endocrinology, Chandigarh, India
Cholecalciferol to Improve the Outcomes of COVID-19 Patients Recruiting • COVID • Vitamin D
• Placebo
• Hospital de Alta Complejidad en Red El Cruce, Florencio Varela, Buenos Aires, Argentina
Do Vitamin D Levels Really Correlated With Disease Severity in COVID-19 Patients? Enrolling by invitation • COVID • vitamin d • Bursa City Hospital, Bursa, Dogankoy, Turkey
Oral 25-hydroxyvitamin D3 and COVID-19 Recruiting • COVID 19 • Oral 25-Hydroxyvitamin D3 • Tehran University of Medical Sciences, Tehran, Iran, Islamic Republic of
Investigating the Role of Vitamin D in the Morbidity of COVID-19 Patients Not yet recruiting • COVID-19
• Vitamin D Deficiency
• Tameside Hospital NHS Foundation Trust, Ashton-under-Lyne, Greater Manchester, United Kingdom
Vitamin D and COVID-19 Management Not yet recruiting • COVID-19 • Ddrops® products, 50,000 IU, Oral
• Vitamin D3
VITACOV: Vitamin D Polymorphisms and Severity of COVID-19 Infection Not yet recruiting • COVID-19 • Exposure • Cardiovascular Center at Universidade de Lisboa, Lisbon, Lisboa, Portugal
• Centro Hospitalar Universitário Lisboa Norte, Lisbon, Lisboa, Portugal
• Centro Hospitalar de São João, Oporto, Portugal
C0vid-19 and Vitamin D Supplementation: a Multicenter Randomized Controlled Trial of High Dose Versus Standard Dose Vitamin D3 in High-risk COVID-19 Patients (CoVitTrial) Recruiting • Coronavirus • cholecalciferol 200,000 IU
• cholecalciferol 50,000 IU
• CHU Angers, Angers, France
• CHU Bordeaux, Bordeaux, France
• CH Le Mans, Le Mans, France
• CHU Lille, Lille, France
• CHU Limoges, Limoges, France
• CHU Nantes, Nantes, France
• CHU Nice, Nice, France
• CHU Saint Etienne, Saint Etienne, France
• CH Saumur, Saumur, France
• CHU Tours, Tours, France
Vitamin D on Prevention and Treatment of COVID-19 Not yet recruiting • Patients Infected With COVID-19 • Vitamin D • Universidad de Granada, Granada, Andalucia, Spain
• Medicine Faculty, Granada, Spain

The Importance of Vitamin D

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  2. Holick MF. The vitamin D deficiency pandemic: a forgotten hormone important for health. Public health reviews. 2010;32(1):267-283.
  3. Amrein K, Scherkl M, Hoffmann M, et al. Vitamin D deficiency 2.0: an update on the current status worldwide. European journal of clinical nutrition. 2020;74(11):1498-1513.
  4. MacLaughlin J, Holick MF. Aging decreases the capacity of human skin to produce vitamin D3. J Clin Invest. 1985;76(4):1536-1538.)
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