UK Biobank recruited 502,624 participants aged 37-73 years across England, Scotland and Wales between 2006 and 2010. At baseline, biological measurements were recorded and touch-screen questionnaires were administered according to a standardized protocol. The total UK Biobank sample included in the current analysis was 353,299 adults with a mean age of 67.7±8.1 years. A total of 192,001 subjects (54.4%) were women and a total of 228,314 subjects (64.6%) were ≥65 years old. Almost two-thirds (67%) of adults in England are overweight or obese. Those of the black, and Asian ethnic groups are more severely affected.