Review the Research  

Get summaries of key research on vitamin D and COVID-19 

Evaluation of the relationship of serum vitamin D levels in COVID-19 patients with clinical course and prognosis.

Take Home Message

This study reports a relationship between vitamin D levels and outcomes on Turkish patients, but few conclusions can be drawn as no intervention took place.

Results

  • Patients infected with COVID-19 had a significantly lower level of vitamin D than the healthy controls.
  • The 20 patients who developed macrophage activation syndrome (MAS) a severe clinical manifestation of respiratory failure, had a lower level of vitamin D compared to 68 patients who did not develop this syndrome.
  • Vitamin D levels of the patients (n= 8) who passed away due to COVID-19, were statistically significantly lower compared to those who survivied.

Who

108 patients who were admitted to the emergency department of Ataturk University and Erzurum Regional Education Research Hospital with complaints of primarily fever, cough, shortness of breath, weakness, sudden taste and smell, who had returned from a visit abroad in the last 14 days and who had been in contact with suspected COVID-19 patient, were included in the study. 20 control patients were also included.

Things to Keep in Mind

This was a single center study, no intervention took place, the vitamin D levels of study subjects may have been influenced by many factors, and there was no control for age and co-morbidities.

Author’s Conclusions

Due to COVID-19, pandemic, long-running quarantines caused insufficient use of sunlight and worsening of vitamin D deficiency. We wanted to draw attention again with our study to vitamin D which can be responsible for the heavy clinical course of COVID-19 and whose replacement is easy to apply.

Study Design

After admission to the clinic, biochemical parameters, clotting parameters, ferritin, D-Dimer, troponin-l, CRP, and arterial blood gas parameters, hematological parameters, liver and kidney function tests were assessed and repeated daily.

Reference

Kerget B, Kerget F, Kızıltunç A, Koçak AO, Araz Ö, Yılmazel Uçar E, Akgün M. Evaluation of the relationship of serum vitamin D levels in COVID-19 patients with clinical course and prognosis. Tuberk Toraks. 2020 Sep;68(3):227-235. English. doi: 10.5578/tt.70027.

View Full Abstract

Research Summaries

Vitamin D status of Arab Gulf residents screened for SARS‑CoV‑2 and its association with COVID‑19 infection: a multi-center case–control study.

Vitamin D status of Arab Gulf residents screened for SARS‑CoV‑2 and its association with COVID‑19 infection: a multi-center case–control study. Take Home Message A total of 220 individuals living in Riyadh,

The Biochemical Parameters and Vitamin D Levels in ICU Patients with Covid-19: A Cross-Sectional Study

The Biochemical Parameters and Vitamin D Levels in ICU Patients with Covid-19: A Cross-Sectional Study. Take Home Message In a cross-sectional study of 118 COVID-19 patients in Iran who required ICU

2021-07-27T11:25:15-05:00