In this study, vitamin D deficiency did not correlate to COVID-19 infection rate. COVID-19 mortality was significantly associated with vitamin D deficiency.
The data from this study provides evidence that vitamin D may have an anti‐inflammatory effect on COVID‐19 patients and vitamin D may provide protective effects.
High prevalence of low vitamin D levels is associated with increased disease severity due to an increased immune-inflammatory response.
Though the results are not significant, Serum levels of 25(OH)D, vitamin B12, and especially zinc at the time of admission can affect clinical outcomes in COVID‐19 patients.
Low UV exposure can affect the required production of vitamin D in the body, which substantially influences the dynamics of COVID-19 transmission and severity.
Supplementation with cholecalciferol or calcifediol helped subject to achieve serum 25OHD levels ≥30 ng/ml which were associated with better COVID-19 outcomes.
Vitamin D deficiency has a significant dose-response relationship with adverse clinical outcomes of COVID-19 infection, including hospitalization and mortality.
Vitamin D levels of healthy children (>6 years old) and adolescents decreased in the first year of the pandemic most likely due to the pandemic-related restrictions.
This systematic review reports that vitamin D supplementation is effective in reducing COVID19 severity
The Impact of Vitamin D Status on COVID-19 Severity among Hospitalized Patients in the Western Region of Saudi Arabia: A Retrospective Cross-Sectional Study
